mesЭкстремальная биомедицинаExtreme Medicine3033-89643033-8972Centre for Strategic Planning of the Federal Medical and Biological Agency10.47183/mes.2023.013mes-133Research ArticleОБЗОРREVIEWРоль радиологических методик и гибридного метода ПЭТ-МРТ в диагностике фармакорезистентной эпилепсииRole of radiology techniques and hybrid PET-MRI technique in the diagnosis of pharmacoresistant epilepsyДолгушинМ. Б.DolgushinM. B.

Москва

Moscow

РостовцеваТ. М.RostovtsevaT. M.

Татьяна Михайловна Ростовцеваул. Островитянова, д. 1, стр. 10, 117513, г. Москва

Tatiana M. RostovtsevaOstovityanov, 1, bld. 10, 117513, Moscow

rostovtsevat@mail.ruДуюноваА. В.DuyunovaA. V.

Москва

Moscow

НаделяевР. В.NadelyaevR. V.

Москва

Moscow

БереговМ. М.BeregovM. M.

Москва

Moscow

Федеральный центр мозга и нейротехнологий Федерального медико-биологического агентстваРоссияFederal Center for Brain and Neurotechnologies of the Federal Medical Biological AgencyRussian Federation2023261020242522132Copyright © Долгушин М.Б., Ростовцева Т.М., Дуюнова А.В., Наделяев Р.В., Берегов М.М., 20242024Долгушин М.Б., Ростовцева Т.М., Дуюнова А.В., Наделяев Р.В., Берегов М.М.Dolgushin M.B., Rostovtseva T.M., Duyunova A.V., Nadelyaev R.V., Beregov M.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.extrememedicine.ru/jour/article/view/133

Результаты хирургического лечения пациентов с фармакорезистентной эпилепсией напрямую зависят от точности диагностики локализации   эпилептогенного очага. Диагностический алгоритм при эпилепсии традиционно начинается с видео-ЭЭГ мониторинга и магнитно-резонансной   томографии. У существенной части пациентов с фармакорезистентной эпилепсией с помощью этих методик не удается локализовать эпилептогенный   очаг либо результаты этих исследований не согласуются между собой. В обзоре представлен анализ данных литературы о современных возможностях   методов ОФЭКТ, ПЭТ и новой гибридной методики ПЭТ-МРТ в предоперационном планировании пациентов с фармакорезистентной эпилепсией.  

The surgical treatment outcome in patients with pharmacoresistant epilepsy directly depends on the epileptic focus localization accuracy. Conventional diagnostic    algorithms for patients with epilepsy involve starting with video EEG monitoring and magnetic resonance imaging. It is not possible to localize epileptogenic foci with    the use of these techniques in a large segment of patients with pharmacoresistant epilepsy, or the test results are discordant. The review provides the analysis of    literature data on the current possibilities of SPECT, PET and new hybrid PET-MRI technique when used for preoperative planning in patients with refractory epilepsy.   

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The authors declare that there are no conflicts of interest present.