mesЭкстремальная биомедицинаExtreme Medicine3033-89643033-8972Centre for Strategic Planning of the Federal Medical and Biological Agency10.47183/mes.2023.028mes-53Research ArticleОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕORIGINAL RESEARCHОсобенности биоэлектрической активности ретросплениальной коры головного мозгаFeatures of bioelectric activity of the retrosplenial cortexГуляевС. А.GulyaevS. A.

Сергей Александрович Гуляев

Раменки, д. 31, к. 136, г. Москва, 119607

Sergey A. Gulyaev

Ramenki, 31, k. 136, Moscow, 119607 

s.gulyaev73@gmail.comХануховаЛ. М.KhanukhovaL. M.

Москва

Moscow

ГармашА. А.GarmashA. A.

Москва

Moscow

Инженерно-физический институт биомедицины Национального исследовательского ядерного университета «МИФИ»; Клиника Ла СалютеРоссияInstitute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhI; La Salute ClinicRussian FederationКлиника Ла СалютеРоссияLa Salute ClinicRussian FederationИнженерно-физический институт биомедицины Национального исследовательского ядерного университета «МИФИ»РоссияInstitute for Physics and Engineering in Biomedicine, National Research Nuclear University MEPhIRussian Federation202323102024253129136Copyright © Гуляев С.А., Ханухова Л.М., Гармаш А.А., 20242024Гуляев С.А., Ханухова Л.М., Гармаш А.А.Gulyaev S.A., Khanukhova L.M., Garmash A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.extrememedicine.ru/jour/article/view/53

Головной мозг человека представляет собой один из самых сложных для исследования органов. Огромный интерес представляет возможность разработки технологий, обладающих достаточной научной точностью и экономической доступностью при полном соблюдении морально-этических норм человеческого сообщества. Целью работы было изучить возможность исследования активности структур ретросплениальной коры (RSC) на основе ЭЭГ-анализа биоэлектрической активности головного мозга в альфа-диапазоне частот у 36 здоровых добровольцев возрастом в среднем 29,1 года, не имевших острых и хронических заболеваний центральной нервной системы в стадии обострения, тяжелых черепно-мозговых травм, психических заболеваний и эпилепсии. Получены статистически достоверные локализации источников с помощью решения обратной ЭЭГ-задачи, позволяющие использовать их для идентификации биоэлектрической активности структур ретросплениальной коры головного мозга. Применение данной технологии позволит расширить объем исследований функциональной активности головного мозга как в научных, так и клинических учреждениях, создав условия для понимания особенностей работы мозговых структур в условиях физиологической нормы и при наличии психических заболеваний, основу которых составляют различные функциональные изменения головного мозга.

Human brain is one of the most difficult organs to study. The possibility of developing the technologies that have sufficient scientific accuracy and economic accessibility and never violate the moral and ethical standards of human society is of great interest. The study was aimed to study the possibility of assessing the retrosplenial cortex (RSC) structures’ activity based on the EEG analysis of brain activity in the alpha frequency range in 36 healthy volunteers with an average age of 29.1 years, no acute central nervous system disorders or exacerbation of chronic central nervous system disorders, severe traumatic brain injuries, mental disorders or epilepsy. Significant source localizations were obtained by solving the EEG inverse problem that could be used for identification of the cerebral retrosplenial cortex structures’ bioelectric activity. The use of such technology will allow us to expand the scope of the research focused on assessing the brain functional activity in both research and clinical centers, thereby paving the way for understanding the features of the brain structures’ activity in physiologically normal conditions and in individuals with mental disorders caused by various functional alterations in the brain.

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The authors declare that there are no conflicts of interest present.