Application of alginate polymer polysaccharide hemostatic hydrogel for ongoing arterial bleeding from peptic ulcer of gastroenteroanastomosis (A clinical case)

Introduction. Treatment of ulcer gastroduodenal bleeding is a challenging problem of emergency surgery. The combined technique of endoscopic hemostasis in ongoing arterial ulcer bleeding reduces the rate of recurrences in only 21.3% of cases, which indicates the need for improved endoscopic hemostasis technologies. In this regard, the use of triple therapy based on conventional methods (injections, coagulation, clipping) and local hemostatic systems seems promising.

Clinical case description. We describe a clinical case of ongoing arterial ulcer bleeding from a peptic ulcer of gastroenteroanastomosis treated by endoscopic hemostasis using a 5% solution of aminocaproic acid with adrenaline in combination with argon plasma coagulation and pneumatic insufflation of an alginate polymer polysaccharide hemostatic hydrogel on the bleeding site.

Conclusions. The use of a personalized approach to endoscopic hemostasis of arterial bleeding from peptic ulcer of gastroenteroanastomosis using an alginate polymer polysaccharide hemostatic hydrogel as part of combined therapy improves the treatment outcome by ensuring final hemostasis, avoiding emergency surgery for massive bleeding, and facilitating the healing process of the ulcerous defect.

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