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Pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection

https://doi.org/10.47183/mes.2021.017

Abstract

Despite the low incidence, low mortality and relatively mild symptoms of COVID-19 in children, there has been a rise in pediatric patients who develop a condition resembling Kawasaki disease after COVID-19 or contact with individuals infected with SARS-CoV-2. This condition is known as the pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS). This review introduces the reader to the hypotheses of PIMS-TS pathogenesis, provides information about its diagnosis and treatment, presents clinical and laboratory data and describes treatments strategies used in children and adolescents hospitalized to the intensive care unit of the Pediatric Research and Clinical Center for Infectious Diseases. Besides, the review outlines the main diagnostic and prognostic challenges of PIMS-TS.

About the Authors

Yu. V. Lobzin
Pediatric Research and Clinical Center for Infectious Diseases of FMBA; Mechnikov North-West State Medical University; Kirov Military Medical Academy
Russian Federation

Saint Petersburg



A. N. Uskov
Pediatric Research and Clinical Center for Infectious Diseases of FMBA
Russian Federation

Saint Petersburg



N. V. Skripchenko
Pediatric Research and Clinical Center for Infectious Diseases of FMBA; Saint Petersburg State Pediatric Medical University
Russian Federation

Saint Petersburg



A. A. Vilnits
Pediatric Research and Clinical Center for Infectious Diseases of FMBA; Saint Petersburg State Pediatric Medical University
Russian Federation

Alla A. Vilnits

Professora Popova, 9, Saint Petersburg, 197022



M. K. Bekhtereva
Pediatric Research and Clinical Center for Infectious Diseases of FMBA; Saint Petersburg State Pediatric Medical University
Russian Federation

Saint Petersburg



I. V. Babachenko
Pediatric Research and Clinical Center for Infectious Diseases of FMBA; Saint Petersburg State Pediatric Medical University
Russian Federation

Saint Petersburg



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Review

For citations:


Lobzin Yu.V., Uskov A.N., Skripchenko N.V., Vilnits A.A., Bekhtereva M.K., Babachenko I.V. Pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection. Extreme Medicine. 2021;23(2):13-19. https://doi.org/10.47183/mes.2021.017

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