Multipotent mesenchymal stem cells: prospects for use in the treatment of injuries sustained in the Far North
https://doi.org/10.47183/mes.2024.029
Abstract
The review compares promising approaches to treatment of skin and bone tissue injuries sustained under extreme conditions that employ mesenchymal stem cells. The materials have been extracted from Google Scholar and PubMed. We describe key factors of the Arctic region that affect human epidermis and bone tissues, as well as those that complicate their healing in case of injury. The reviewed papers allowed identifying promising products that have a multifaceted effect on the tissue repair processes, which are those employing mesenchymal stem cells, their exosomes, and recombinant growth factors in combination with biomaterials. Medical products developed for treatment of injuries sustained in the Arctic conditions can be used for wounds sustained in other extreme environments.
Supporting agencies: The authors express their gratitude to Jan Borisovich Kovalevsky, General Director of Orion Chemical Company, for his assistance in writing the article.
About the Authors
M. V. Volkova
National Medical Research Center for Rehabilitation and Balneology
Russian Federation
Russian Federation
Marina Viktorovna Volkova
Novy Arbat, 32, Moscow, 121099
P. S. Eremin
National Medical Research Center for Rehabilitation and Balneology
Russian Federation
Russian Federation
Novy Arbat, 32, Moscow, 121099
P. A. Markov
National Medical Research Center for Rehabilitation and Balneology
Russian Federation
Russian Federation
Novy Arbat, 32, Moscow, 121099
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Review
For citations:
Volkova M.V., Eremin P.S., Markov P.A. Multipotent mesenchymal stem cells: prospects for use in the treatment of injuries sustained in the Far North. Extreme Medicine. 2024;26(2):5-12. https://doi.org/10.47183/mes.2024.029
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