Вопрос сохранения интериктальной активности в длительных ЭЭГ-исследованиях эпилепсии
https://doi.org/10.47183/mes.2024.020
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Аннотация
Современное применение математических методов анализа ЭЭГ-записей ограничено из-за феномена усреднения информации. В этих условиях актуально найти наиболее вероятный метод повышения качества диагностики пароксизмальных патологических паттернов, имеющих малую продолжительность «жизни», таких как вспышки и субклинические пароксизмы. Целью исследования было оценить возможность исключения межприступной интериктальной активности из длительного ЭЭГ-исследования для достижения его информационного «обогащения» путем формирования условной последовательностей патологических изменений, представляющих его главную клиническую задачу. Было обследовано 40 человек разного возраста, обоих полов. В контрольную группу вошли 20 пациентов 12–67 лет с непосредственным выявлением спайк-волновой активности на ЭЭГ. Группу сравнения составили 20 пациентов 10–66 лет с отсутствием спайк-волновой активности в записи. Показано, что интериктальные данные, полученные у пациентов c наличием эпилептиформных феноменов, не представляют значимого интереса для основной группы клинических исследований. Исключение этих данных приводит к «обогащению» информации и за счет последовательного размещения пароксизмальных паттернов позволяет получать не только более компактные результаты обследований патологической составляющей, но и сформировать базу для разработок с использованием технологий их последующего математического анализа.
Об авторах
С. А. Гуляев
Инженерно-физический институт биомедицины НИЯУ МИФИ; Клиника Ла Салюте
Россия
Россия
Сергей Александрович Гуляев
ул. Раменки, д. 31, к. 136, г. Москва, 119607
С. Г. Климанов
Инженерно-физический институт биомедицины НИЯУ МИФИ
Россия
Россия
ул. Раменки, д. 31, к. 136, г. Москва, 119607
Г. А. Гермашев
Инженерно-физический институт биомедицины НИЯУ МИФИ
Россия
Россия
ул. Раменки, д. 31, к. 136, г. Москва, 119607
Л. М. Ханухова
Клиника Ла Салюте
Россия
Россия
ул. Раменки, д. 31, к. 136, г. Москва, 119607
А. А. Гармаш
Инженерно-физический институт биомедицины НИЯУ МИФИ
Россия
Россия
ул. Раменки, д. 31, к. 136, г. Москва, 119607
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Рецензия
Для цитирования:
Гуляев С.А., Климанов С.Г., Гермашев Г.А., Ханухова Л.М., Гармаш А.А. Вопрос сохранения интериктальной активности в длительных ЭЭГ-исследованиях эпилепсии. Медицина экстремальных ситуаций. 2024;26(2):140-145. https://doi.org/10.47183/mes.2024.020
For citation:
Gulyaev S.A., Klimanov S.G., Germashev G.A., Khanukhova L.M., Garmash A.A. The issue of preserving interictal activityin long-term EEG studies of epilepsy. Extreme Medicine. 2024;26(2):140-145. https://doi.org/10.47183/mes.2024.020
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ISSN 2713-2765 (Online)
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